Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles

Virtual Cocrystal Screening of Adefovir Dipivoxyl: Identification of New Solid Forms with Improved Dissolution and Permeation Profiles

The application of a computational screening methodology based on the calculation of intermolecular interaction energies has guided the discovery of new multicomponent solid forms of the oral antiviral Adefovir Dipivoxyl. Three new cocrystals with resorcinol, orcinol and hydroquinone have been synth...

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Bibliographic Details
Main Authors: Rafael Barbas (Author), Hanan Fael (Author), Samuel Lee (Author), Rebeca Ruiz (Author), Christopher A. Hunter (Author), Elisabet Fuguet (Author), Clara Ràfols (Author), Rafel Prohens (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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