MTBSTFA derivatization-LC-MS/MS approach for the quantitative analysis of endogenous nucleotides in human colorectal carcinoma cells

• Main Authors: Huixia Zhang (Author), Yan Li (Author), Zheng Li (Author), Christopher Wai-Kei Lam (Author), Peng Zhu (Author), Caiyun Wang (Author), Hua Zhou (Author), Wei Zhang (Author)
• Format: Book
• Published: Elsevier, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Endogenous ribonucleotides (RNs) and deoxyribonucleotides (dRNs) are important metabolites related to the pathogenesis of many diseases. In light of their physiological and pathological significances, a novel and sensitive pre-column derivatization method with N-(t-butyldimethylsilyl)-N-methyltriflu...