Synthesis and biological evaluation of novel N-(piperazin-1-yl)alkyl-1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential MEK inhibitors

In this paper, a series of novel 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid bearing different N-(piperazin-1-yl)alkyl side chains were designed, synthesised and evaluated for their in vitro anticancer activities against three human hepatocarcinoma cell lines (SMMC-7721, HepG2 and He...

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Main Authors: Hao Chen (Author), Chao Qiao (Author), Ting-Ting Miao (Author), A-Liang Li (Author), Wen-Yan Wang (Author), Wen Gu (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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