Squamosamide Derivative FLZ Diminishes Aberrant Mitochondrial Fission by Inhibiting Dynamin-Related Protein 1

• Main Authors: Hanyu Yang (Author), Lu Wang (Author), Caixia Zang (Author), Xu Yang (Author), Xiuqi Bao (Author), Junmei Shang (Author), Zihong Zhang (Author), Hui Liu (Author), Cheng Ju (Author), Fangyuan Li (Author), Fangyu Yuan (Author), Dan Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitochondrial dysfunction is involved in the pathogenesis of Parkinson's disease (PD). Mitochondrial morphology is dynamic and precisely regulated by mitochondrial fission and fusion machinery. Aberrant mitochondrial fragmentation, which can result in cell death, is controlled by the mitochondr...