Variability of the Genes Involved in the Cellular Redox Status and Their Implication in Drug Hypersensitivity Reactions

• Main Authors: Pedro Ayuso (Author), Elena García-Martín (Author), José A. G. Agúndez (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2021-02-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Adverse drug reactions are a major cause of morbidity and mortality. Of the great diversity of drugs involved in hypersensitivity drug reactions, the most frequent are non-steroidal anti-inflammatory drugs followed by β-lactam antibiotics. The redox status regulates the level of reactive oxygen and...