Development and Optimization of a New Chemoenzymatic Approach for the Synthesis of Peracetylated Lactosamine (Intermediate for the Synthesis of Pharmacologically Active Compounds) Monitored by RP- HPLC Method

• Главные авторы: Qais Ibrahim Abualassal (Автор), Khaldun Mohammad Al Azzam (Автор), Zead Helmi Abudayeh (Автор), Loay Khaled Hassouneh (Автор)
• Формат: ‌
• Опубликовано: Tabriz University of Medical Sciences, 2017-06-01T00:00:00Z.
• Предметы: article
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Purpose: To describe a chemoenzymatic approach joining an enzymatic regioselective hydrolysis of peracetylated N-acetyl-α-D-glucosamine (A) with a mild controlled acyl relocation which resulted 2-acetamido-2 deoxy-1,3,6-tri-O-acetyl-α-D-glucopyranose (1B). Methods: Immobilization of lipase on decaoc...