Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics

• Autori principali: Rahul Khetan (Autore), Robin Curtis (Autore), Charlotte M. Deane (Autore), Johannes Thorling Hadsund (Autore), Uddipan Kar (Autore), Konrad Krawczyk (Autore), Daisuke Kuroda (Autore), Sarah A. Robinson (Autore), Pietro Sormanni (Autore), Kouhei Tsumoto (Autore), Jim Warwicker (Autore), Andrew C.R. Martin (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Therapeutic monoclonal antibodies and their derivatives are key components of clinical pipelines in the global biopharmaceutical industry. The availability of large datasets of antibody sequences, structures, and biophysical properties is increasingly enabling the development of predictive models an...