Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation

Background. Human bone marrow stromal/stem cells (hMSCs, also known as the skeletal stem cells or mesenchymal stem cells) are being employed to study lineage fate determination to osteoblasts, adipocytes, and chondrocytes. However, mechanistic studies employing hMSC have been hampered by the difficu...

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Main Authors: Li Chen (Author), Kaikai Shi (Author), Weimin Qiu (Author), Lars Aagaard (Author), Moustapha Kassem (Author)
Format: Book
Published: Hindawi Limited, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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