Evaluating the Role of Neddylation Modifications in Kidney Renal Clear Cell Carcinoma: An Integrated Approach Using Bioinformatics, MLN4924 Dosing Experiments, and RNA Sequencing

• Main Authors: Dequan Liu (Author), Guangzhen Wu (Author), Shijin Wang (Author), Xu Zheng (Author), Xiangyu Che (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2024-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Background: Neddylation, a post-translational modification process, plays a crucial role in various human neoplasms. However, its connection with kidney renal clear cell carcinoma (KIRC) remains under-researched. Methods: We validated the Gene Set Cancer Analysis Lite (GSCALite) platform against The...