The 'New (Nu)-clear' evidence of the tumor-driving role of PI3K

The classical phosphatidylinositol 3-kinases (PI3Ks) are heterodimers of p110 and p85. PIK3CA, the gene encoding the catalytic p110α subunit, is one of the most frequently mutated oncogenes in human cancers. Mutations have been observed to occur in hotspots in the helical domain or kinase domain. Tu...

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Bibliographic Details
Main Authors: Franklin Mayca Pozo (Author), Tony Hunter (Author), Youwei Zhang (Author)
Format: Book
Published: Compuscript Ltd, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
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