Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle

• Main Authors: Philipp Rhein (Author), Eric M. Desjardins (Author), Ping Rong (Author), Danial Ahwazi (Author), Nicolas Bonhoure (Author), Jens Stolte (Author), Matthieu D. Santos (Author), Ashley J. Ovens (Author), Amy M. Ehrlich (Author), José L. Sanchez Garcia (Author), Qian Ouyang (Author), Julian M. Yabut (Author), Mads Kjolby (Author), Mathieu Membrez (Author), Niels Jessen (Author), Jonathan S. Oakhill (Author), Jonas T. Treebak (Author), Pascal Maire (Author), John W. Scott (Author), Matthew J. Sanders (Author), Patrick Descombes (Author), Shuai Chen (Author), Gregory R. Steinberg (Author), Kei Sakamoto (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The metabolic master-switch AMP-activated protein kinase (AMPK) mediates insulin-independent glucose uptake in muscle and regulates the metabolic activity of brown and beige adipose tissue (BAT). The regulatory AMPKγ3 isoform is uniquely expressed in skeletal muscle and potentially in BAT...