Abigene, a Prospective, Multicentric Study of Abiraterone Acetate Pharmacogenetics in Metastatic Castration-Resistant Prostate Cancer

• Principais autores: Jean-Marc Ferrero (Autor), Hakim Mahammedi (Autor), Gwenaelle Gravis (Autor), Guilhem Roubaud (Autor), Philippe Beuzeboc (Autor), Remi Largillier (Autor), Delphine Borchiellini (Autor), Claude Linassier (Autor), Nathalie Ebran (Autor), Tanguy Pace-Loscos (Autor), Marie-Christine E (Autor), Renaud Schiappa (Autor), Jocelyn Gal (Autor), Gérard Milano (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2023-02-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abiraterone acetate (AA) is the first-in-class of drugs belonging to the second-generation of agents inhibiting androgen neosynthesis in advanced prostate cancer. A cumulative experience attests that germinal gene polymorphisms may play a role in the prediction of anticancer agent pharmacodynamics v...