Abigene, a Prospective, Multicentric Study of Abiraterone Acetate Pharmacogenetics in Metastatic Castration-Resistant Prostate Cancer

• Main Authors: Jean-Marc Ferrero (Author), Hakim Mahammedi (Author), Gwenaelle Gravis (Author), Guilhem Roubaud (Author), Philippe Beuzeboc (Author), Remi Largillier (Author), Delphine Borchiellini (Author), Claude Linassier (Author), Nathalie Ebran (Author), Tanguy Pace-Loscos (Author), Marie-Christine E (Author), Renaud Schiappa (Author), Jocelyn Gal (Author), Gérard Milano (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abiraterone acetate (AA) is the first-in-class of drugs belonging to the second-generation of agents inhibiting androgen neosynthesis in advanced prostate cancer. A cumulative experience attests that germinal gene polymorphisms may play a role in the prediction of anticancer agent pharmacodynamics v...