Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autoradiography: Implication for the local treatment of Stargardt's disease and dry age‐related macular degeneration

• Prif Awduron: Sylvie Julien‐Schraermeyer (Awdur), Barbara Illing (Awdur), Alexander Tschulakow (Awdur), Tatjana Taubitz (Awdur), Jamil Guezguez (Awdur), Michael Burnet (Awdur), Ulrich Schraermeyer (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Wiley, 2020-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract Age‐related macular degeneration (AMD) is the leading cause of blindness in older people in the developed world while Stargardt's disease (SD) is a juvenile macular degeneration and an orphan disease. Both diseases are untreatable and are marked by accumulation of lipofuscin advancing...