Newborn Screening Protocols and Positive Predictive Value for Congenital Adrenal Hyperplasia Vary across the United States

• Main Authors: Phyllis W. Speiser (Author), Reeti Chawla (Author), Ming Chen (Author), Alicia Diaz-Thomas (Author), Courtney Finlayson (Author), Meilan M. Rutter (Author), David E. Sandberg (Author), Kim Shimy (Author), Rashida Talib (Author), Jane Cerise (Author), Eric Vilain (Author), Emmanuèle C. Délot (Author)
• Format: Book
• Published: MDPI AG, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Newborn screening for congenital adrenal hyperplasia (CAH) caused by 21-hydroxylase deficiency is mandated throughout the US. Filter paper blood specimens are assayed for 17-hydroxyprogesterone (17OHP). Prematurity, low birth weight, or critical illness cause falsely elevated results. The purpose of...