On the three-finger protein domain fold and CD59-like proteins in Schistosoma mansoni.

• Main Authors: Leonardo P Farias (Author), Greice Krautz-Peterson (Author), Cibele A Tararam (Author), Bogar O Araujo-Montoya (Author), Tatiana R Fraga (Author), Henrique K Rofatto (Author), Floriano P Silva (Author), Lourdes Isaac (Author), Akram A Da'dara (Author), R Alan Wilson (Author), Charles B Shoemaker (Author), Luciana C C Leite (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

It is believed that schistosomes evade complement-mediated killing by expressing regulatory proteins on their surface. Recently, six homologues of human CD59, an important inhibitor of the complement system membrane attack complex, were identified in the schistosome genome. Therefore, it is importan...