A potent novel vaccine adjuvant based on straight polyacrylate

• Main Authors: Marie Garinot (Author), Fabienne Piras-Douce (Author), Patricia Probeck (Author), Véronique Chambon (Author), Kucku Varghese (Author), Yuanqing Liu (Author), Ernesto Luna (Author), Donald Drake (Author), Jean Haensler (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A structure-activity study was conducted to identify the structural characteristics underlying the adjuvant activity of straight (i.e. non-crosslinked) polyacrylate polymers (PAAs) in order to select a new PAA adjuvant candidate for future clinical development. The study revealed that the adjuvant e...