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From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome

SUMMARY Apert syndrome is a congenital disorder characterized by severe skull malformations and caused by one of two missense mutations, S252W and P253R, on fibroblast growth factor receptor 2 (FGFR2). The molecular bases underlying differential Apert syndrome phenotypes are still poorly understood...

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Bibliographic Details
Main Authors: Neus Martínez-Abadías (Author), Greg Holmes (Author), Talia Pankratz (Author), Yingli Wang (Author), Xueyan Zhou (Author), Ethylin Wang Jabs (Author), Joan T. Richtsmeier (Author)
Format: Book
Published: The Company of Biologists, 2013-05-01T00:00:00Z.
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