PGC-1α isoforms coordinate to balance hepatic metabolism and apoptosis in inflammatory environments

• Main Authors: Mélissa Léveillé (Author), Aurèle Besse-Patin (Author), Nathalie Jouvet (Author), Aysim Gunes (Author), Sarah Sczelecki (Author), Stewart Jeromson (Author), Naveen P. Khan (Author), Cindy Baldwin (Author), Annie Dumouchel (Author), Jorge C. Correia (Author), Paulo R. Jannig (Author), Jonathan Boulais (Author), Jorge L. Ruas (Author), Jennifer L. Estall (Author)
• Format: Book
• Published: Elsevier, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: The liver is regularly exposed to changing metabolic and inflammatory environments. It must sense and adapt to metabolic need while balancing resources required to protect itself from insult. Peroxisome proliferator activated receptor gamma coactivator-1 alpha (PGC-1α) is a transcriptiona...