Accuracy of a dual path platform (DPP) assay for the rapid point-of-care diagnosis of human leptospirosis.

• Main Authors: Scott A Nabity (Author), Guilherme S Ribeiro (Author), Carolina Lessa Aquino (Author), Daniele Takahashi (Author), Alcinéia Oliveira Damião (Author), André H O Gonçalves (Author), Demócrito B Miranda-Filho (Author), Rena Greenwald (Author), Javan Esfandiari (Author), Konstantin P Lyashchenko (Author), Mitermayer G Reis (Author), Marco A Medeiros (Author), Albert I Ko (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Diagnosis of leptospirosis by the gold standard serologic assay, the microscopic agglutination test (MAT), requires paired sera and is not widely available. We developed a rapid assay using immunodominant Leptospira immunoglobulin-like (Lig) proteins in a Dual Path Platform (DPP). This st...