The Adenosine A2A-Receptor Antagonist Istradefylline Enhances the Motor Response of l-DOPA Without Worsening Dyskinesia in MPTP-Treated Common Marmosets

The adenosine A2A-receptor antagonist istradefylline decreases OFF time in patients with Parkinson's disease who are already treated with optimal doses of dopaminergic medication but can cause an increase in non-troublesome dyskinesia. Preclinical experiments have shown that A2A antagonists are...

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Main Authors: Shin-ichi Uchida (Author), Tomomi Tashiro (Author), Mika Kawai-Uchida (Author), Akihisa Mori (Author), Peter Jenner (Author), Tomoyuki Kanda (Author)
Format: Book
Published: Elsevier, 2014-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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