Activation of SIK1 by phanginin A inhibits hepatic gluconeogenesis by increasing PDE4 activity and suppressing the cAMP signaling pathway
Objective: Salt-induced kinase 1 (SIK1) acts as a key modulator in many physiological processes. However, the effects of SIK1 on gluconeogenesis and the underlying mechanisms have not been fully elucidated. In this study, we found that a natural compound phanginin A could activate SIK1 and further i...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2020-11-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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