Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models

• Auteurs principaux: Ludmila A. Alekseeva (Auteur), Aleksandra V. Sen'kova (Auteur), Marina A. Zenkova (Auteur), Nadezhda L. Mironova (Auteur)
• Format: Livre
• Publié: Elsevier, 2020-06-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Tumor-associated cell-free DNAs (cfDNAs) are found to play some important roles at different stages of tumor progression; they are involved in the transformation of normal cells and contribute to tumor migration and invasion. DNase I is considered a promising cancer cure, due to its ability to degra...