Airway β-Defensin-1 Protein Is Elevated in COPD and Severe Asthma

• Main Authors: Katherine J. Baines (Author), Thomas K. Wright (Author), Jodie L. Simpson (Author), Vanessa M. McDonald (Author), Lisa G. Wood (Author), Kristy S. Parsons (Author), Peter A. Wark (Author), Peter G. Gibson (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Innate immune antimicrobial peptides, including β-defensin-1, promote the chemotaxis and activation of several immune cells. The role of β-defensin-1 in asthma and chronic obstructive pulmonary disease (COPD) remains unclear. Methods. Induced sputum was collected from healthy controls an...