Mitochondrial aberrations during the progression of disuse atrophy differentially affect male and female mice

• Main Authors: Megan E. Rosa‐Caldwell (Author), Seongkyun Lim (Author), Wesley S. Haynie (Author), Jacob L. Brown (Author), David E. Lee (Author), Kirsten R. Dunlap (Author), Lisa T. Jansen (Author), Tyrone A. Washington (Author), Michael P. Wiggs (Author), Nicholas P. Greene (Author)
• Format: Book
• Published: Wiley, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Disuse decreases muscle size and is predictive of mortality across multiple pathologies. Detriments to mitochondrial function are hypothesized to underlie disuse‐induced muscle atrophy. Little data exist on early mechanisms contributing to onset of these pathologies, nor is it kn...