Evidence for TGF-β1/Nrf2 Signaling Crosstalk in a Cuprizone Model of Multiple Sclerosis

• Main Authors: Coram Guevara (Author), Sinay C. Vicencio (Author), Ignacio S. Pizarro (Author), Francisca Villavicencio-Tejo (Author), Rodrigo A. Quintanilla (Author), Pablo Astudillo (Author), Estibaliz Ampuero (Author), Rodrigo Varas (Author), Juan A. Orellana (Author), Fernando C. Ortiz (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multiple sclerosis (MS) is a chronic and degenerative disease that impacts central nervous system (CNS) function. One of the major characteristics of the disease is the presence of regions lacking myelin and an oxidative and inflammatory environment. TGF-β1 and Nrf2 proteins play a fundamental role...