Three dimensional distribution of surfactant in microspheres revealed by synchrotron radiation X-ray microcomputed tomography

• Main Authors: Li Wu (Author), Manli Wang (Author), Vikramjeet Singh (Author), Haiyan Li (Author), Zhen Guo (Author), Shuangying Gui (Author), Peter York (Author), Tiqiao Xiao (Author), Xianzhen Yin (Author), Jiwen Zhang (Author)
• Format: Book
• Published: Elsevier, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated the formulation mechanism of microspheres via internal surfactant distribution. Eudragit L100 based microspheres loaded with bovine serum albumin were prepared by solid in oil in oil emulsion solvent evaporation method using acetone and liquid paraffin system containing sucro...