Utility of Physiologically Based Pharmacokinetic Modeling to Investigate the Impact of Physiological Changes of Pregnancy and Cancer on Oncology Drug Pharmacokinetics

Background: The treatment of cancer during pregnancy remains challenging with knowledge gaps in drug dosage, safety, and efficacy due to the under-representation of this population in clinical trials. Our aim was to investigate physiological changes reported in both pregnancy and cancer populations...

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Hauptverfasser: Xinxin Yang (VerfasserIn), Manuela Grimstein (VerfasserIn), Michelle Pressly (VerfasserIn), Elimika Pfuma Fletcher (VerfasserIn), Stacy Shord (VerfasserIn), Ruby Leong (VerfasserIn)
Format: Buch
Veröffentlicht: MDPI AG, 2023-12-01T00:00:00Z.
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