2D-QSAR and CoMFA Models for Antitubercular Activity of Scalarane-Type Sesterterpenes

• Hauptverfasser: Suriyan Thengyai (Verfasst von), Yuewei Guo (Verfasst von), Khanit Suwanborirux (Verfasst von), Heinz Berner (Verfasst von), Helmut Spreitzer (Verfasst von), Peter Wolschann (Verfasst von), Supa Hannongbua (Verfasst von), Anuchit Plubrukarn (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2022-08-01T00:00:00Z.
• Schlagworte: article
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A series of scalarane sesterterpenes were prepared using heteronemin (<b>1</b>) as a primary precursor. Combined with the scalarane derivatives obtained from natural sources, a total of 22 antitubercular scalaranes were used to build QSAR models based in the 2D-QSAR and CoMFA approaches....