A thermosensitive gel based on w1/o/w2 multiple microemulsions for the vaginal delivery of small nucleic acid

• Principais autores: Jiu Wang (Autor), Yajing Wang (Autor), Ziqiang Wang (Autor), Fan Wang (Autor), Jie He (Autor), Xiaoyun Yang (Autor), Weidong Xie (Autor), Ying Liu (Autor), Yaou Zhang (Autor)
• Formato: Livro
• Publicado em: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The present study aims at designing a thermosensitive gel prepared from w1/o/w2 multiple microemulsions (MMEs) for the vaginal delivery of siRNA. The w1/o/w2 MMEs were prepared by two-step emulsifications: the first step was to prepare primary emulsions (w1/o) by low energy emulsification (LEE); the...