A thermosensitive gel based on w1/o/w2 multiple microemulsions for the vaginal delivery of small nucleic acid

• Main Authors: Jiu Wang (Author), Yajing Wang (Author), Ziqiang Wang (Author), Fan Wang (Author), Jie He (Author), Xiaoyun Yang (Author), Weidong Xie (Author), Ying Liu (Author), Yaou Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study aims at designing a thermosensitive gel prepared from w1/o/w2 multiple microemulsions (MMEs) for the vaginal delivery of siRNA. The w1/o/w2 MMEs were prepared by two-step emulsifications: the first step was to prepare primary emulsions (w1/o) by low energy emulsification (LEE); the...