A Triphenylphosphonium-Functionalized Mitochondriotropic Nanocarrier for Efficient Co-Delivery of Doxorubicin and Chloroquine and Enhanced Antineoplastic Activity

• Main Authors: Katerina N. Panagiotaki (Author), Zili Sideratou (Author), Spiros A. Vlahopoulos (Author), Maria Paravatou-Petsotas (Author), Michael Zachariadis (Author), Nikolas Khoury (Author), Vassilis Zoumpourlis (Author), Dimitris Tsiourvas (Author)
• Format: Book
• Published: MDPI AG, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug delivery systems that target subcellular organelles and, in particular, mitochondria are considered to have great potential in treating disorders that are associated with mitochondrial dysfunction, including cancer or neurodegenerative diseases. To this end, a novel hyperbranched mitochondriotr...