A Triphenylphosphonium-Functionalized Mitochondriotropic Nanocarrier for Efficient Co-Delivery of Doxorubicin and Chloroquine and Enhanced Antineoplastic Activity

• Κύριοι συγγραφείς: Katerina N. Panagiotaki (Συγγραφέας), Zili Sideratou (Συγγραφέας), Spiros A. Vlahopoulos (Συγγραφέας), Maria Paravatou-Petsotas (Συγγραφέας), Michael Zachariadis (Συγγραφέας), Nikolas Khoury (Συγγραφέας), Vassilis Zoumpourlis (Συγγραφέας), Dimitris Tsiourvas (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2017-11-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Drug delivery systems that target subcellular organelles and, in particular, mitochondria are considered to have great potential in treating disorders that are associated with mitochondrial dysfunction, including cancer or neurodegenerative diseases. To this end, a novel hyperbranched mitochondriotr...