Characterization of N-Linked Glycosylation in a Monoclonal Antibody Produced in NS0 Cells Using Capillary Electrophoresis with Laser-Induced Fluorescence Detection

The N-linked glycosylation in recombinant monoclonal antibodies (mAb) occurs at Asn297 on the Fc region in the CH2 domain. Glycosylation heterogeneities have been well documented to affect biological activities such as antibody-dependent cellular cytotoxicity (ADCC) and complement-dependent cytotoxi...

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Váldodahkkit: Yang Wang (Dahkki), Melissa Hamm (Dahkki), Richard R. Rustandi (Dahkki)
Materiálatiipa: Girji
Almmustuhtton: MDPI AG, 2013-03-01T00:00:00Z.
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3rd Floor Main Library

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