ANTITROMBOTIC ACTIVITY OF A NEW BENZIMIDAZOLE DERIVATIVE WITH A SPATIALLY DIFFICULT PHENOLIC SUBSTITUTE IN ITS STRUCTURE

• Main Authors: Alexander A. Spasov (Author), Aida F. Kucheryavenko (Author), Ksenia A. Gaidukova (Author), Maxim V. Chernikov (Author), Olga N. Zhukovskaya (Author)
• Format: Book
• Published: Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of the study was to investigate antithrombogenic properties of compound RU-1144 with previously identified pronounced antiplatelet and antioxidant activities. The thrombosis induced by Ferric chloride (FeCl3) was carried out in rats' carotid artery, in comparison with the known antiaggr...