Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease.

• Главные авторы: Philip M Giffard (Автор), Steven Y C Tong (Автор), Deborah C Holt (Автор), Anna P Ralph (Автор), Bart J Currie (Автор)
• Формат: ‌
• Опубликовано: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Предметы: article
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The prevalence of rheumatic heart disease (RHD) in the Aboriginal population of the Australian Northern Territory is high, and Streptococcus pyogenes skin infections likely contribute to this. A promising candidate S. pyogenes "30mer" vaccine is composed of 30 pharyngitis associated type-s...