Basal and regulatory promoter studies of the aldo-keto reductase 1C3 (AKR1C3) gene in relation to prostate cancer

• Główni autorzy: Jenny J Schulze (Autor), Helena eKarypidis (Autor), Lena eEkström (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2012-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: Human 17-hydroxysteroid dehydrogenase type 5 (17-HSD5) formally known as aldo-keto reductase 1C3 (AKR1C3) play a major role in the formation and metabolism of androgens. The enzyme is highly expressed in the prostate gland and previous studies indicate that genetic variation in the AKR...