Impacts of GFP-FoxP3+ regulatory T cells on lupus hallmarks differ by genetic background and type of GFP knock-in

• Main Authors: Soog-Hee Chang (Author), Tae-Joo Kim (Author), Yongbaek Kim (Author), Seung Seok Han (Author), Sun-Kyung Lee (Author), Ji Hyun Sim (Author), Young-Joo Kim (Author), Se Jeong Lee (Author), Im Joo Rhyu (Author), Ki-Hoan Nam (Author), Chandra Mohan (Author), Hang-Rae Kim (Author)
• Format: Book
• Published: Taylor & Francis Group, 2019-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

FoxP3 reporter mice expressing green fluorescence protein (GFP) have been used as a very convenient tool to investigate the impact of regulatory T (Treg) cells on pathogenesis in autoimmune diseases. Here, we found that GFP-FoxP3+ knock-in (KI) mice showed alterations in the production of anti-nucle...