NF1 deficiency drives metabolic reprogramming in ER+ breast cancer
Objective: NF1 is a tumor suppressor gene and its protein product, neurofibromin, is a negative regulator of the RAS pathway. NF1 is one of the top driver mutations in sporadic breast cancer such that 27 % of breast cancers exhibit damaging NF1 alterations. NF1 loss-of-function is a frequent event i...
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Main Authors: | , , , , , , , , , , |
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Format: | Book |
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Elsevier,
2024-02-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
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A1234.567 |
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Copy 1 | Available |