Comprehensive understanding of the adverse effects associated with temozolomide: a disproportionate analysis based on the FAERS database

• Main Authors: Yusen Zhou (Author), Peng Jia (Author), Yuting Fang (Author), Wei Zhu (Author), Yong Gong (Author), Tianyu Fan (Author), Jiangliu Yin (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundTemozolomide, which is the standard drug for glioma treatment, has several Adverse events (AEs) in the treatment of gliomas and other tumors that are not yet fully understood. This is due to the pharmacological nature of the alkylating agent. A significant proportion of these effects have...