Interrelationship between Changes in the Amyloid β 42/40 Ratio and Presenilin 1 Conformation

Abstract The ratio of the longer (Aβ42/Aβ43) to shorter (Aβ40) species is a critical factor determining amyloid fibril formation, neurotoxicity and progression of the amyloid pathology in Alzheimer's disease. The relative levels of the different Aβ species are affected by activity and conformat...

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Main Authors: Katarzyna Marta Zoltowska (Author), Masato Maesako (Author), Oksana Berezovska (Author)
Format: Book
Published: BMC, 2016-07-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
Copy 1 Available