Trichinella spiralis paramyosin binds to C8 and C9 and protects the tissue-dwelling nematode from being attacked by host complement.

• Glavni autori: Zhifei Zhang (Autor), Jing Yang (Autor), Junfei Wei (Autor), Yaping Yang (Autor), Xiaoqin Chen (Autor), Xi Zhao (Autor), Yuan Gu (Autor), Shijuan Cui (Autor), Xinping Zhu (Autor)
• Format: Knjiga
• Izdano: Public Library of Science (PLoS), 2011-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

BACKGROUND: Paramyosin is a thick myofibrillar protein found exclusively in invertebrates. Evidence suggested that paramyosin from helminths serves not only as a structural protein but also as an immunomodulatory agent. We previously reported that recombinant Trichinella spiralis paramyosin (Ts-Pmy)...