The Inhibition of Phosphoinositide-3 Kinases Induce Resolution of Inflammation in a Gout Model

• Main Authors: Izabela Galvão (Author), Celso Martins Queiroz-Junior (Author), Vivian Louise Soares de Oliveira (Author), Vanessa Pinho (Author), Emilio Hirsch (Author), Mauro Martins Teixeira (Author)
• 格式: 圖書
• 出版: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Phosphoinositide-3 kinases (PI3Ks) are central signaling enzymes that are involved in many aspects of immune cell function. PI3Kγ and PI3Kδ are the major isoforms expressed in leukocytes. The role of PI3K isoforms in the resolution of inflammation is still poorly understood. Here, we investigated th...