Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis.

• Autores principales: Doumet Georges Helou (Autor), Aurélie Mauras (Autor), François Fasquelle (Autor), Juliane Sousa Lanza (Autor), Philippe M Loiseau (Autor), Didier Betbeder (Autor), Sandrine Cojean (Autor)
• Formato: Libro
• Publicado: Public Library of Science (PLoS), 2021-08-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Visceral leishmaniasis is a protozoan disease associated with high fatality rate in developing countries. Although the drug pipeline is constantly improving, available treatments are costly and live-threatening side effects are not uncommon. Moreover, an approved vaccine against human leishmaniasis...