Intranasal vaccine from whole Leishmania donovani antigens provides protection and induces specific immune response against visceral leishmaniasis.

• Main Authors: Doumet Georges Helou (Author), Aurélie Mauras (Author), François Fasquelle (Author), Juliane Sousa Lanza (Author), Philippe M Loiseau (Author), Didier Betbeder (Author), Sandrine Cojean (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Visceral leishmaniasis is a protozoan disease associated with high fatality rate in developing countries. Although the drug pipeline is constantly improving, available treatments are costly and live-threatening side effects are not uncommon. Moreover, an approved vaccine against human leishmaniasis...