IL-1 and its role in rat carrageenan pleurisy

• Main Authors: R. Goodman (Author), L. R. Mantegna (Author), C. L. McAIlister (Author), E. Bruin (Author), R. L. Dowling (Author), H. George (Author), W. Feeser (Author), B. Freimark (Author), M. Lischwe (Author), S. Pick (Author), R. R. Harris (Author), J. S. Kerr (Author)
• Format: Book
• Published: Hindawi Limited, 1993-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The carrageenan pleurisy model, which is characterized by cellular influx and oedema, has been used to examine the effects of anti-inflammatory compounds such as naproxen. Interleukin-1α and β (IL-1) are known to be pro-inflammatory mediators, and their roles in this model are unknown. Intrapleural...