Lobeglitazone Attenuates Airway Inflammation and Mucus Hypersecretion in a Murine Model of Ovalbumin-Induced Asthma

• Main Authors: Na-Rae Shin (Author), Sung-Hyeuk Park (Author), Je-Won Ko (Author), Young-Kwon Cho (Author), In-Chul Lee (Author), Jong-Choon Kim (Author), In-Sik Shin (Author), Joong-Sun Kim (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lobeglitazone (LB) is a novel agonist of peroxisome proliferator-activated receptor (PPAR)-α and γ that was developed as a drug to treat diabetes mellitus. We explored the ameliorative effects of LB on allergic asthma using a murine model of ovalbumin (OVA)-induced asthma. To boost the immune respon...