DNA-protein immunization using Leishmania peroxidoxin-1 induces a strong CD4+ T cell response and partially protects mice from cutaneous leishmaniasis: role of fusion murine granulocyte-macrophage colony-stimulating factor DNA adjuvant.

To date, no universally effective and safe vaccine has been developed for general human use. Leishmania donovani Peroxidoxin-1 (LdPxn-1) is a member of the antioxidant family of proteins and is predominantly expressed in the amastigote stage of the parasite. The aim of this study was to evaluate the...

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Main Authors: Abebe Genetu Bayih (Author), Nada S Daifalla (Author), Lashitew Gedamu (Author)
Format: Book
Published: Public Library of Science (PLoS), 2014-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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