Dupilumab Effects on Innate Lymphoid Cell and Helper T Cell Populations in Patients with Atopic Dermatitis

• Asıl Yazarlar: Yasutomo Imai (Yazar), Minori Kusakabe (Yazar), Makoto Nagai (Yazar), Koubun Yasuda (Yazar), Kiyofumi Yamanishi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2021-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Group 2 innate lymphoid cells (ILCs) are thought to contribute to the pathogenesis of atopic dermatitis (AD). IL-4 stimulates T helper type 2 (Th2) cells and ILC2s to proliferate and produce cytokines. Dupilumab, an antibody against the IL-4 receptor, is used in AD therapy. We speculated that its ef...