Xanthates As Useful Probes for Testing the Active Sites of Cytochromes P450 4A11 and 2E1
Xanthates (alkyl or aryl derivatives of dithiocarbonic acid) have been shown to be selective mechanism-based inactivators of cytochromes P450 2B1/2B6 and 2E1 due to covalent binding of a reactive intermediate to apoprotein after double hydrogen abstraction at α-carbon atom, suggesting interaction of...
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Frontiers Media S.A.,
2017-09-01T00:00:00Z.
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A1234.567 |
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