Xanthates As Useful Probes for Testing the Active Sites of Cytochromes P450 4A11 and 2E1

Xanthates (alkyl or aryl derivatives of dithiocarbonic acid) have been shown to be selective mechanism-based inactivators of cytochromes P450 2B1/2B6 and 2E1 due to covalent binding of a reactive intermediate to apoprotein after double hydrogen abstraction at α-carbon atom, suggesting interaction of...

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Main Authors: Tsveta Stoyanova (Author), Iglika Lessigiarska (Author), Momir Mikov (Author), Ilza Pajeva (Author), Stanislav Yanev (Author)
Format: Book
Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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