Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease

• Main Authors: Wenxu Pan (Author), Li Xiang (Author), Xinhua Liang (Author), Wenjun Du (Author), Junhong Zhao (Author), Song Zhang (Author), Xuan Zhou (Author), Lanlan Geng (Author), Sitang Gong (Author), Wanfu Xu (Author)
• Format: Book
• Published: Hindawi Limited, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. Vitronectin (VTN) has been reported to trigger cell pyroptosis to aggravate inflammation in our previous study. However, the function of VTN in inflammatory bowel disease (IBD) remains to be addressed. Methods. Real-time PCR and western blotting were performed to analyze VTN-regulated int...