Persistent infection due to a small-colony variant of Burkholderia pseudomallei leads to PD-1 upregulation on circulating immune cells and mononuclear infiltration in viscera of experimental BALB/c mice.

• Main Authors: Jia-Xiang See (Author), Samudi Chandramathi (Author), Mahmood Ameen Abdulla (Author), Jamuna Vadivelu (Author), Esaki M Shankar (Author)
• 格式: 圖書
• 出版: Public Library of Science (PLoS), 2017-08-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

Melioidosis is a neglected tropical disease endemic across South East Asia and Northern Australia. The etiological agent, Burkholderia pseudomallei (B.pseudomallei), is a Gram-negative, rod-shaped, motile bacterium residing in the soil and muddy water across endemic regions of the tropical world. Th...