Research Progress on Natural Diterpenoids in Reversing Multidrug Resistance

• Main Authors: Zhuo-fen Deng (Author), Irina Bakunina (Author), Hua Yu (Author), Jaehong Han (Author), Alexander Dömling (Author), Maria-José U Ferreira (Author), Jian-ye Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Multidrug resistance (MDR) is one of the main impediments in successful chemotherapy in cancer treatment. Overexpression of ATP-binding cassette (ABC) transporter proteins is one of the most important mechanisms of MDR. Natural products have their unique advantages in reversing MDR, among which dite...